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KMID : 0363320190400030458
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Journal of Korean Oriental Internal Medicine
2019 Volume.40 No. 3 p.458 ~ p.477
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A Review of Domestic Research on Traditional Korean Medicine for Alcoholic Liver Disease
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Cho Na-Kyung
Lee Yu-Ri
Kim Kyung-Soon
Choi Hong-Sik
Kim Seung-Mo
Back Young-Doo
Moon Byung-Kwon
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Abstract
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Objectives: This study aimed to investigate the trend in the research on alcoholic liver disease (ALD) using Korean traditional medicine.
Methods: This review was conducted using six electronic databases (NDSL, KMBASE, Koreantk, KISS, KISTI, and KoreaMed) with no restrictions in year. The search terms were “alcoholic liver disease”, “alcoholic fatty liver”, “alcoholic hepatitis”, “alcoholic cirrhosis”, “herbal medicine”, “acupuncture” and “traditional medicine”. The searched studies were analyzed according to the type of research.
Results: After screening, 37 studies were selected among 552. The types of studies were as follows: 8 in vivo studies, 17 case reports, 7 case series, 1 assessment scale study, 1 randomized controlled trial, and 3 research reviews. The in vivo studies reported the efficacy and its mechanism in the animal phase of single or complex herbal medicine. In the clinical research, interventions such as herbal medicine and acupuncture were most commonly used for ALD treatment.
Conclusions: We analyzed the trends in ALD treatment using Korean traditional medicine through this review. The results showed that Korean traditional medicine could be an effective method for ALD treatment. Conducting related in-depth studies, such as well-designed randomized controlled trial based on the results of experimental research, is necessary.
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KEYWORD
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alcoholic liver disease, traditional medicine, review
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